For about two centuries, Seville was one of the richest cities in Europe. After Columbus, every ship that sailed to the Americas had to leave from here and every ounce of silver that came back had to be registered here, and the city filled up with churches, palaces and painters to match. Before that it was Isbiliya, a capital of the Moorish Almohads, who left behind the minaret that is now the Giralda, and before that a Roman town, close to Itálica, where the families of two emperors, Trajan and Hadrian, came from. You'll see all of it in the first two days.
Seville is also the Spain of the postcards, and it doesn't mind: flamenco, bullfighting, Holy Week processions, the April Fair, horse carriages, tiled patios and orange trees on every street. But it's a working city of 700,000 people who eat late, talk loudly and spend a lot of their lives standing at a bar with a small plate and a cold drink. Five days is the right amount: enough for the big sights, a day trip to Córdoba and time to live at Seville's pace.
This plan keeps each day in one part of town. Day one is the Cathedral, the Alcázar and the old Jewish quarter of Santa Cruz, day two Plaza de España, the river and Triana, day three the palaces and tapas bars of the north of the old town, day four a trip to Córdoba, and day five the Roman city of Itálica and the riverbanks. Because a few museums close on Mondays, the plan works best if day one is a Tuesday. Carmona, Jerez, Cádiz and Ronda come after day five. For the bigger picture, see our page on Spain.